Drugs That Treat Multiple Conditions: Hydroxyzine
Throughout the pharmaceutical world, there are numerous drugs that help people manage multiple conditions. Topiramate, developed to treat seizures, doubles as a migraine treatment. Bupropion, typically prescribed as an antidepressant, also aids in smoking cessation. Minoxidil, developed to treat high blood pressure, is perhaps better known for reversing hair loss.
Clinical trials determine the effectiveness and safety of drugs before they’re approved for public use, but sometimes these trials reveal unforeseen benefits. Hydroxyzine is a prominent example of this type of versatile medication, and one we’ll explore its multiple uses in this article.
Hydroxyzine: A Versatile Medication
Hydroxyzine, a prescription antihistamine typically administered orally, has applications beyond stopping runny noses. As an antihistamine, hydroxyzine is commonly used as a treatment for allergies and allergic reactions, such as certain types of eczema, dermatitis, hay fever, asthma and conjunctivitis. Its additional uses include:
- Anxiety treatment
- Sedation before medical procedures
- Nausea and vomiting relief
- Motion sickness symptom alleviation
Some studies, including those conducted by UF Health, also suggest that the anti-inflammatory response of hydroxyzine lowers the risk of death among hospitalized COVID-19 patients.
How Hydroxyzine Works
Hydroxyzine, an H1-blocker, impedes the effects of histamine, a chemical produced within the human immune system. It crosses the blood-brain barrier and interacts with serotonin and dopamine receptors, producing sedative and anxiety-reducing effects.
H1-blockers such as hydroxyzine stop histamines from binding to histamine receptors, which can be found throughout the body, including on glandular and mast cells, smooth muscle, and nerves. Histamines widen blood vessels and make them more permeable, leading to fluid leakage from capillaries into adjacent tissues. H1-blockers prevent these actions, effectively reducing inflammation and alleviating allergy symptoms.
If an inflammatory condition leads to chronic inflammation, treatment is essential for the prevention of damage to organs and DNA and the development of several serious diseases, including cancer and heart disease.
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The University of Florida’s online Master of Science in Medical Sciences with a concentration in Medical Physiology and Pharmacology explores how various drugs and substances affect body systems and overall human health. Our 30-credit program enables you to gain crucial knowledge and a valued credential that can lead to a rewarding career as a:
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Sources:
https://www.mayoclinic.org/drugs-supplements/hydroxyzine-oral-route/description/drg-20311434
https://my.clevelandclinic.org/health/drugs/20775-hydroxyzine-solution
https://my.clevelandclinic.org/health/articles/24854-histamine
https://health.usnews.com/wellness/slideshows/8-medications-that-treat-multiple-conditions?slide=9
https://www.aocd.org/page/antihistamines?
