Category: Physiology
How Do Vitamins Work? The Science Behind Their Absorption
Many of the foods we eat naturally contain vitamins and other nutrients, while others are fortified, such as milk with added vitamin D. Still, some people lack certain essential vitamins due to their diet, age, gender, genetics or other factors. To compensate, many take supplements, such as multivitamins, that deliver a variety of vitamins and minerals in every dose.
How do vitamins work in the body? Let’s explore this topic and examine the ongoing controversy surrounding supplement efficacy within medical and scientific communities.
How Do Vitamin Supplements Travel Through Your Body?
Here’s a step-by-step explanation of how vitamins travel through the human body:
- You swallow the vitamin supplement, and it moves down the esophagus to the stomach.
- In the stomach, digestion begins. Digestive acids and enzymes begin to dissolve the supplement, but it’s not fully digested here.
- The remaining portion travels to the small intestine, where it’s further broken down by digestive enzymes and fluids from the liver and pancreas.
- In the second and third parts of the small intestine, nutrients from the digested supplement are absorbed into the intestinal lining. From here, the method of entry into the bloodstream depends on the type of vitamin:
- Water-soluble vitamins (B and C) are absorbed directly into the bloodstream.
- Fat-soluble vitamins (A, D, E and K) must be broken down by bile acids before being absorbed. These are then absorbed by the lymphatic system and transported into the bloodstream.
- The bloodstream carries the beneficial portions of the vitamin to various cells and tissues in the body.
- Excess water-soluble vitamins and their byproducts exit the body through urine, while remaining fat-soluble vitamins are stored in the liver and fatty tissues for later use.
What Is the Role of Vitamins in Our Bodies?
Vitamins play crucial roles throughout the body, aiding each organ, tissue and cell in different ways. They help:
- Fight infections
- Improve vision
- Build strong bones and muscles
- Regulate hormones
Many cells in our bodies, from skin to bone, regenerate regularly to replace old and damaged ones. For example, the outer layer of our skin cells renews about once a month. This regeneration process requires vitamins, whether obtained from food or supplements, making them essential to the normal, healthy functioning of the body.
What’s the Controversy Behind Vitamin Supplements?
While taking vitamin supplements may seem beneficial, many experts argue that vitamins in supplement form provide little to no health value compared to those obtained through food. Some point to scant evidence that supplements prevent or cure any major diseases.
Others contend that the body does absorb beneficial vitamins from supplements but eliminates excess amounts through urination — a potentially favorable scenario. Most experts agree that the best way to obtain vitamins is through a nutrient-rich diet rather than supplements.
Fortify Your Career with a Master of Science from UF
Vitamins, drugs and other compounds can profoundly impact the major human body systems. We examine their beneficial and detrimental effects in the University of Florida’s online Master of Science in Medical Sciences with a concentration in Medical Physiology and Pharmacology, offered through our College of Medicine.
Built around an MCAT-aligned curriculum, our 30-credit MS program prepares you for medical school or nursing school admission and a variety of rewarding careers in medicine, science, pharmacy and research.
- Earn your master’s degree entirely online — no campus or lab visits required.
- Get started with no GRE requirement.
- Complete coursework at your own pace from practically any location.
- Maintain your professional commitments.
- Transfer up to 15 credits from a qualifying UF graduate certificate program.
- Finish your degree in as little as two semesters.
Add a respected master’s degree to your career credentials. Apply today!
Sources:
https://ods.od.nih.gov/factsheets/WYNTK-Consumer/
https://www.hopkinsmedicine.org/health/wellness-and-prevention/is-there-really-any-benefit-to-multivitamins
https://www.prevention.com/life/a20474960/how-to-make-sure-youre-benefiting-from-your-vitamins/
https://health.clevelandclinic.org/which-vitamins-should-you-take
https://my.clevelandclinic.org/health/body/7041-digestive-system
https://time.com/6171584/are-vitamins-supplements-healthy/
Drugs That Treat Multiple Conditions: Hydroxyzine
Throughout the pharmaceutical world, there are numerous drugs that help people manage multiple conditions. Topiramate, developed to treat seizures, doubles as a migraine treatment. Bupropion, typically prescribed as an antidepressant, also aids in smoking cessation. Minoxidil, developed to treat high blood pressure, is perhaps better known for reversing hair loss.
Clinical trials determine the effectiveness and safety of drugs before they’re approved for public use, but sometimes these trials reveal unforeseen benefits. Hydroxyzine is a prominent example of this type of versatile medication, and one we’ll explore its multiple uses in this article.
Hydroxyzine: A Versatile Medication
Hydroxyzine, a prescription antihistamine typically administered orally, has applications beyond stopping runny noses. As an antihistamine, hydroxyzine is commonly used as a treatment for allergies and allergic reactions, such as certain types of eczema, dermatitis, hay fever, asthma and conjunctivitis. Its additional uses include:
- Anxiety treatment
- Sedation before medical procedures
- Nausea and vomiting relief
- Motion sickness symptom alleviation
Some studies, including those conducted by UF Health, also suggest that the anti-inflammatory response of hydroxyzine lowers the risk of death among hospitalized COVID-19 patients.
How Hydroxyzine Works
Hydroxyzine, an H1-blocker, impedes the effects of histamine, a chemical produced within the human immune system. It crosses the blood-brain barrier and interacts with serotonin and dopamine receptors, producing sedative and anxiety-reducing effects.
H1-blockers such as hydroxyzine stop histamines from binding to histamine receptors, which can be found throughout the body, including on glandular and mast cells, smooth muscle, and nerves. Histamines widen blood vessels and make them more permeable, leading to fluid leakage from capillaries into adjacent tissues. H1-blockers prevent these actions, effectively reducing inflammation and alleviating allergy symptoms.
If an inflammatory condition leads to chronic inflammation, treatment is essential for the prevention of damage to organs and DNA and the development of several serious diseases, including cancer and heart disease.
Master Drug Mechanisms and Advance Your Medical Sciences Career
The University of Florida’s online Master of Science in Medical Sciences with a concentration in Medical Physiology and Pharmacology explores how various drugs and substances affect body systems and overall human health. Our 30-credit program enables you to gain crucial knowledge and a valued credential that can lead to a rewarding career as a:
- Physician
- Physician assistant
- Nurse
- Clinical scientist
- Professor
- Researcher
Our program’s MCAT-aligned curriculum helps prepare you for admission to medical school or nursing school and can distinguish you among a wide field of candidates in a highly competitive admissions environment where about 60% of medical school applicants are rejected annually.
Benefits of Online Learning
As an online student, you’ll complete your degree entirely online. No campus or lab visits are required. This empowers you to:
- Access coursework from practically anywhere.
- Work at your own pace.
- Connect with classmates and faculty anytime through email, discussion groups and other online tools.
- Network with students from the U.S. and around the world for broader career prospects.
- Earn a graduate credential while meeting your professional and personal obligations.
Start Sooner and Finish Faster
Our online master’s degree in medical physiology and pharmacology program does not require GRE scores, enabling you to bypass that common admission step. And you can collect your online master’s degree in medical physiology and pharmacology sooner — in as little as two semesters — if you’ve already completed a qualifying UF graduate certificate program. We allow you to transfer up to 15 credits to this MS program from your:
Choose an Institution Acclaimed for Quality
This master’s degree program is bolstered by UF’s exceptional reputation and accolades:
- Liaison Committee on Medical Education (LCME)-accredited College of Medicine
- Renowned faculty comprised of the same accomplished researchers and physicians who teach UF’s medical students
- Acknowledgements including:
Prime yourself for greater opportunities ahead. Apply now!
Sources:
https://www.mayoclinic.org/drugs-supplements/hydroxyzine-oral-route/description/drg-20311434
https://my.clevelandclinic.org/health/drugs/20775-hydroxyzine-solution
https://my.clevelandclinic.org/health/articles/24854-histamine
https://health.usnews.com/wellness/slideshows/8-medications-that-treat-multiple-conditions?slide=9
https://www.aocd.org/page/antihistamines?
How Does Nicotine Replacement Therapy Relieve Addiction?
”From a scientific standpoint, nicotine is just as hard, or harder, to quit than heroin.” This jarring statement from nicotine researcher Dr. Neil Benowitz may explain why so many people struggle with giving up nicotine for years, or even a lifetime.
When individuals use conventional cigarettes, cigars, chewing tobacco or e-cigarettes, the bloodstream quickly absorbs the chemical nicotine and transports it to the brain. The brain responds by releasing dopamine, the “happy hormone,” producing a pleasurable sensation. The body eventually grows accustomed to that sensation and becomes dependent on nicotine to produce it. When a smoker quits cigarettes, they may begin to feel angrier, sadder and hungrier due to the lack of stimulation from nicotine. They start to crave that happy hormone feeling. This is nicotine addiction.
Viable Alternatives to Nicotine
Overcoming nicotine addiction is no easy task for many. But there are substitutes for nicotine that are designed to wean addicts off of this harmful substance. In 1984, nicotine addicts found a new hope as the Food and Drug Administration (FDA) approved nicotine replacement therapy (NRT). NRT products were first introduced in the form of gum, then later patches, lozenges, inhalers and other methods. Many of these were originally offered by prescription only but subsequently became available over the counter.
NRTs act upon the receptors in the brain that are affected by nicotine, easing the cravings and withdrawal symptoms that most people who give up nicotine experience. Quite often, using multiple NRT methods at the same time yields better results. According to researchers, NRTs boost tobacco quit rates by up to 70%. In most cases, therapy involves gradually reducing the amount of nicotine and/or frequency of the use of NRT until the user is weaned off the addictive chemical altogether.
It should be noted that while many nicotine users are able to overcome their physiological dependence on nicotine through NRT, such products do not alleviate any behavioral associations that tobacco users develop. For example, some smokers associate pleasure with the act of picking up a cigarette and placing it in their mouth or just feeling the sensation of having a cigarette between the lips. For this reason, behavioral therapy is often recommended alongside or following NRT.
Master Physiology and Pharmacology Online
The University of Florida’s renowned College of Medicine provides degree and certificate programs that will help you understand how nicotine and other substances can impact human physiology and broaden your knowledge of body systems overall. Each of these programs is presented entirely online, which allows you to complete a respected education credential on your own schedule, around any professional and personal responsibilities you may have. All programs are available 24/7 from just about any location.
Master of Science in Medical Sciences with a concentration in Medical Physiology and Pharmacology
Our online master’s degree in medical physiology and pharmacology program explores the major human body systems and how different drugs impact and are impacted by them. In addition, our program helps you prepare for National Board, MCAT and other key exams that can enable you to advance into a new role in your medical career. You may be able to finish this program in as little as one year.
What’s more, if you have completed a Graduate Certificate in Medical Physiology or a Graduate Certificate in Medical Physiology with a specialization in Cardiovascular/Renal Physiology (more information below), you’re already halfway to earning a master’s degree in medical physiology and pharmacology. Our 30-credit degree program accepts up to 15 credits from these UF graduate certificate programs. Consider the advantages of our master’s degree in medical physiology and pharmacology program:
- Earn your master’s degree in as little as one year.
- Complete coursework at your own pace.
- Build clinical knowledge that can help you excel in medical school.
- Get started without taking the GRE.
- Use financial aid options, if needed.
- Add a career-defining education credential to your resume.
Graduate Certificate in Medical Physiology
Our Graduate Certificate in Medical Physiology investigates the fundamentals of the field and explores individual systems of the human body. You can take as many as six courses in this 9- to 14-credit program, though you are only required to complete 9 credits. That means you may be able to complete the program in a single semester.
Graduate Certificate in Medical Physiology with a specialization in Cardiovascular/Renal Physiology
We also offer a Graduate Certificate in Medical Physiology with a specialization in Cardiovascular/Renal Physiology, an advanced-level look at cardiovascular and renal physiology and pathophysiology that you’ll find invaluable in a clinical setting. You can complete this 12-credit program in as little as two semesters.
Find out how the human body functions and interacts with different drugs and other substances in an entirely online master’s degree or graduate certificate program from the University of Florida.
Sources:
https://www.psychologytoday.com/us/basics/dopamine
https://www.drugabuse.gov/publications/research-reports/tobacco-nicotine-e-cigarettes/nicotine-addictive
https://www.cancer.org/healthy/stay-away-from-tobacco/guide-quitting-smoking/nicotine-replacement-therapy.html
https://www.verywellmind.com/nicotine-replacement-therapy-4013217
https://www.sciencedaily.com/releases/2016/08/160831085320.htm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003586/
https://www.healthline.com/health/oral-fixation#examples-in-adults
Becoming an Astronaut: How Space Flight Affects Our Bodies
As children, many of us shared a similar professional goal: We were determined to become astronauts. Little did we know that NASA’s acceptance rate is abysmally low. In 2024, more than 8,000 people applied to become astronauts. Of that number, NASA will only choose between eight and 12 candidates.
Beyond the rigorous selection process, one aspect of being an astronaut that we likely didn’t consider as children is the effect space flight has on our bodies. With drastic changes in gravity and no atmosphere to shield us from the sun’s UV rays, several short- and long-term changes can occur in our bodies while in space.
Settle in and buckle up as we explore the effects of space flight on humans and — for those still interested — the prerequisites for becoming an astronaut.
Immediate Effects During Launch
In addition to the adrenaline spike they may feel during the famed countdown to liftoff, astronauts may experience several other physiological changes during space shuttle launches due to increased G-forces, including:
- Difficulty moving limbs.
- Tunnel vision or brief loss of consciousness.
- A reduced ability for the heart to efficiently pump blood.
- Bodily fluids shifting upward, which can cause fluid retention in the upper body.
- Discomfort in the sinuses due to changes in air pressure.
Musculoskeletal Adaptations
If you’re on a commercial mission to space, you’ll likely only be there long enough to appreciate the beauty of Earth from above, notice its curvature and maybe even experience a few sunsets or sunrises, depending on your positioning. Astronauts on extended missions will remain in space much longer. The average duration of an astronaut’s mission aboard the International Space Station (ISS) is 6 months.
Half a year is plenty of time for the lack of gravity to take a toll on your musculoskeletal system (i.e., your muscles and bones). On Earth, your body constantly uses its muscles to resist the force of gravity. In space, however, there’s no gravity to fight, so you end up using your muscles significantly less.
Over time, living in a zero-gravity atmosphere can weaken your muscles and reduce bone mass. Fortunately, astronauts can mitigate the effects of these unique conditions before, during and after a mission by engaging in a rigorous exercise routine. During their time on the ISS, astronauts exercise for about two hours a day, strengthening their bodies by using a treadmill and incorporating strength training.
Changes to the Immune System
Having lived on Earth your entire life, your immune system has adapted to function under Earth’s gravitational pull. Experiencing altered gravity in space impairs your immune system’s peak performance. In addition to microgravity, increased radiation and disrupted circadian rhythms can also impact your immune system.
A weakened immune system might result in your body fighting harder and longer to combat an infection it could easily overcome on Earth. You might also become more susceptible to infections until you return to Earth’s normal conditions and your immune system readjusts.
Psychological and Cognitive Effects
Physical changes aren’t the only effects to expect while spending an extended period in space. Being away from family and in constant close quarters with the same small group of people for months can impact your mental well-being, leading to feelings of isolation or confinement.
Astronauts prepare for these psychological effects through several strategies, including:
- Undergoing psychological resilience training before the mission.
- Participating in simulated missions to acclimate to the cognitive demands of space travel.
- Establishing a structured daily routine while in space to maintain normalcy.
- Contacting family regularly via email and video calls.
- Bringing personal items and participating in group activities and hobbies aboard the ISS.
- Having regular check-ins and psychological assessments.
Do You Have What It Takes for a Trip to Space?
While astronauts face several mental and physical hurdles as they embark on expeditions in space, they’re also pioneering scientific research that could change the future of science, technology and the way we live. Although many people believe they have what it takes to become an astronaut, it requires more than just determination. In addition to being a U.S. citizen and having a minimum of three years of related professional experience, you need a master’s degree in a STEM field from an accredited institution.
Whether you aspire to become an astronaut or you’re interested in turning your fascination with the human body into a lucrative career, the University of Florida offers several online graduate programs ideal for those interested in advancing their careers in health and sciences:
Our online programs in medical physiology, offered by one of U.S. News’ top 50 national universities, also boast the following benefits:
- Affordable tuition rates.
- Year-round start dates.
- No GRE requirement.
- Flexible coursework completion on your timeline.
Take the first step in advancing your career in the expansive and profitable world of STEM — apply today!
Sources:
https://touroscholar.touro.edu/cgi/viewcontent.cgi?article=1077&context=sjlcas
https://www.kennedyspacecenter.com/blog/the-20-most-frequently-asked-questions-about-the-international-space-station
https://www.nasa.gov/missions/station/scientists-probe-how-long-term-spaceflight-alters-immunity/
https://www.abc.net.au/news/health/2024-03-09/preparing-human-mind-space-travel-mars-astronauts-mission/103563280
Sleep Physiology: The Restorative Power of Rest
We spend about one-third of our lives asleep, making it no surprise that sleep is a favorite activity for many. Yet, few of us consider the internal processes at work as we settle into bed and drift into dreamland.
This is where sleep physiology comes into play. It delves into the biological processes behind sleep, exploring how our bodies regulate it, its effects on bodily functions and the different stages of sleep.
So, grab your favorite pillow and join us as we uncover the essentials of sleep physiology and discover how to enhance your sleep habits for optimal rest and renewal.
The Sleep Cycle
Each night, we cycle through two primary phases of sleep:
- Nonrapid Eye Movement (NREM)
NREM sleep accounts for approximately 75% of your sleep time and consists of three stages:- Stage one: This brief phase occurs as you start to fall asleep and lasts about five minutes.
- Stage two: After we nod off, we enter a light sleep for around 25 minutes.
- Stage three: This is the deepest phase of NREM and often the hardest to wake from. Waking up during this phase can lead to mental fogginess and reduced performance for up to an hour. It is also the most restorative phase, where the body repairs tissues and boosts the immune system.
- Rapid Eye Movement (REM)
Following NREM, REM sleep begins with rapid eye movements and accounts for about 25% of your total sleep time. This phase is famous for creating vivid dreams — like that one where your cat juggled baby mice before a crowd of elderly lions in 1980s punk rock gear. Despite its rich dream content, REM sleep is the least restorative phase.
Throughout the night, we cycle through these two phases, with the first NREM cycle lasting about 70 minutes and lengthening with each subsequent cycle. The initial REM cycle lasts around 10 minutes, with later cycles extending up to an hour. In total, we experience approximately four to six sleep cycles a night.
Effects of Impaired Sleep
Have you ever struggled through a few rough nights of sleep? Whether it’s due to caring for a new baby or giving in to that third cup of coffee, various factors can lead to restless nights.
You might have noticed the effects of impaired sleep, like difficulty retaining new information, decreased coordination or mood swings. If so, you’re not alone. According to the National Council on Aging, 30% of Americans suffer from insomnia, and 10% say it affects their daily lives.
Psychological risks of continued poor sleep may include:
- Hallucinations
- Mania
- Impulsive behavior
- Anxiety
- Depression
- Paranoia
- Suicidal thoughts
The Benefits of Restorative Rest
We’ve all experienced waking up from a blissful eight (or even ten) hours of solid sleep. On those mornings, we often feel well-rested, with increased mental clarity, heightened energy and a renewed drive to tackle the day. Oh, the power of a good night’s sleep.
While sleep needs vary based on genetics, adults aged 18 to 60 generally require seven or more hours each night to experience the following benefits:
- Improved immune response
- Reduced stress levels
- Enhanced metabolism
- Better heart health
- Lower risk of chronic conditions, such as Type 2 diabetes, high blood pressure and stroke
- Improved attention span
- Greater ability to remember information
Tips for Optimizing Sleep
Even under the best circumstances, not every night will provide the perfect amount of zzz’s — but you can still significantly increase the number of nights you enjoy rejuvenating rest. Here are some tips to improve the quality of your sleep:
- Establish a bedtime routine
Go to bed at the same time each night. Develop a consistent pre-sleep routine, such as showering, brushing your teeth and reading a book in bed, to help you wind down and prepare for rest.
- Maintain a sleep-positive environment
Minimize auditory distractions by closing the door or using a sound machine. Maintain a cool room temperature to enhance thermoregulation, which may help you remain in REM sleep for longer periods.
- Turn off electronic devices before bed
While scrolling through social media or catching up on news might seem like a relaxing end to your day, the blue light emitted by phones can interfere with sleep. Instead, replace screen time with relaxing activities like journaling, meditating, stretching or reading.
Turn Your Passion Into a Rewarding Career
If you’re intrigued by what your brain and body are up to while you sleep, or if you’re considering a career dedicated to improving the sleep health of others, there are several paths to explore within this segment of the healthcare industry.
The University of Florida offers a variety of online graduate programs in the medical sciences designed to help you achieve your professional goals. These programs provide an excellent foundation, whether you’re ready to enter the workforce or plan to apply to professional school for further education.
Explore the online graduate certificates and master’s degrees below to find the program that best suits your interests and career aspirations.
Benefits of earning a graduate credential with UF include:
- Earning many of these credentials in as little as one year.
- Completing the program at your own pace.
- Working on assignments from anywhere, anytime.
- Applying without GRE scores required.
- Enrolling in programs with year-round admission.
- Receiving an education from one of U.S. News’ top 50 national universities.
With so many online graduate credentials to choose from, the choice is yours. Which program aligns with the future of your dreams? Apply today!
Sources:
https://www.healthline.com/health/sleep-deprivation/effects-on-body#effects
https://www.ncoa.org/adviser/sleep/sleep-statistics/
https://www.ncbi.nlm.nih.gov/books/NBK526132/
https://www.cdc.gov/sleep/about/index.html
https://health.clevelandclinic.org/what-is-the-ideal-sleeping-temperature-for-my-bedroom
https://www.sleepfoundation.org/how-sleep-works/how-electronics-affect-sleep
Gut Flora 101: Key Functions of Gut Bacteria and Health Tips
This very second, you have trillions of microorganisms living inside your body — so many that they make up one to three percent of your entire body weight! While you have a sizable combination of bacteria, fungi and viruses swarming around inside you, most microbial cells in your body consist of different types of bacteria, many of them residing in your gut.
All those gut bacteria have a handful of important jobs to do, including protecting you against pathogens and helping you digest food, which can be especially helpful if you got a little too excited at the all-you-can-eat pizzeria last weekend. Prepare to thank all those tiny bacteria for their hard work as we discuss the important functions that gut bacteria play in our everyday lives and review some tips to help you improve your gut flora.
What Is Gut Bacteria?
While you have microbes living on your skin and throughout your body, most of them are bacteria that live in your large intestine, small intestine and stomach. Also known as gut bacteria, this gargantuan number of tiny organisms goes by several other names as well, including:
- Microflora
- Microbiome
- Microbiota
- Intestinal flora
- Gut flora
Regardless of which moniker you use, they all refer to approximately 1,000 species of bacteria that populate your gut, each responsible for various roles in your body. But you’re not born with all these microbes in your body. A baby in utero has an almost entirely sterile gut. It’s not until they make their way through the birth canal that they receive the mother’s vaginal bacteria. While this might not sound glamorous, it’s exactly what a baby needs to begin forming a healthy gut microbiome.
What Are the Functions of Gut Bacteria?
In recent years, microbiologists have spent an increasing amount of time determining the role that intestinal flora play in our health. With so many bacteria inside our intestines, it only makes sense that they are somehow significant, right?
Scientific research shows that gut bacteria may be responsible for multiple roles in our bodies, including the ones listed below.
Digesting Food
Some of the first bacteria that babies grow in their gut are called Bifidobacteria. This type of microbe helps us digest the healthy sugars found in breast milk and promotes growth. As our gut flora become more advanced, they help us digest other forms of nutrients too, including:
- Fiber
- Complex carbohydrates (like whole grains and vegetables)
- Proteins
- Vitamin K
Supporting Your Immune System
Some of the bacteria in your gut help line your large intestines to keep harmful substances — and leaky gut syndrome — at bay. Helpful bacteria may also work in tandem with your immune system to help fight against pathogen-causing bacteria and communicate with immune cells to control how your body reacts to infection.
Influencing Brain Function
Have you ever experienced a case of “the butterflies” in your stomach before a big test or a nerve-wracking first date? According to the American Psychological Association, your gut is tied to your mood, ability to learn, memory and emotions. So, when you find yourself “going with your gut,” it might be because you’re using your second brain — a.k.a. your gut bacteria’s independent nervous system — to help you make some of your decisions.
In addition, your brain and gut are connected through neurotransmitters. Often produced in your brain, these chemicals are responsible for controlling your feelings and emotions. For example, serotonin is a neurotransmitter that provides feelings of happiness. Not to be outdone, your gut also produces serotonin as well as gamma-aminobutyric acids (GABA), which help regulate negative emotions like anxiety or fear.
Does Gut Bacteria Also Cause Health Issues?
Yes, maintaining an unhealthy diet and not getting adequate sleep increases your risk of altering your gut flora’s composition. If you find yourself with an imbalance of the healthy microbes in the gut, it may contribute to certain health problems, such as:
- Obesity
- Diabetes
- Inflammatory bowel disease (IBD)
- Inflammatory bowel syndrome (IBS)
- Metabolic syndrome
How to Improve Gut Flora: Quick Tips
If you find yourself with more harmful than healthy bacteria, there is a light at the end of the tunnel. With a few changes to your diet, you can begin rebuilding the healthy bacteria in your microbiome. Below are a few tips to implement to get your gut health back on track:
- Eat a healthy combination of macronutrients such as complex carbs, healthy fats and lean protein.
- Opt for fermented foods like yogurt, sauerkraut and kimchi. They all contain the healthy bacteria Lactobacilli, which may lessen disease-causing bacteria in the gut.
- Incorporate prebiotic foods like artichokes, asparagus, oats and bananas. They stimulate the growth of healthy gut bacteria.
- Only take antibiotics when necessary. While they work to kill bacteria-causing infections in your body, they also kill good bacteria.
You’re not the only one who takes gut health seriously — so does the University of Florida. Our online graduate certificate programs allow you to develop an in-depth comprehension and mastery of the fundamental concepts in several areas of medical sciences, preparing you for numerous careers in healthcare, education, public health and more.
In addition to acquiring the skills that will provide a leg up against the competition, our 12-credit certificate offers multiple benefits for working professionals, including:
- Entirely online courses
- Classes available year-round
- No GRE requirement
- Affordable tuition
Apply to the program that aligns with your future plans today.
Sources:
https://www.nih.gov/news-events/news-releases/nih-human-microbiome-project-defines-normal-bacterial-makeup-body
https://www.amnh.org/exhibitions/the-secret-world-inside-you/microbiome-at-birth
https://www.healthline.com/nutrition/gut-microbiome-and-health#TOC_TITLE_HDR_2
https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-019-0704-8
https://www.apa.org/monitor/2012/09/gut-feeling
https://www.healthline.com/nutrition/gut-brain-connection
https://www.verywellhealth.com/what-are-your-gut-flora-1944914
How Does Ozempic Work for Diabetes? A Complete Breakdown
In the United States, approximately 38 million people have diabetes. Within that population, about 95% have type 2 diabetes, a condition that affects your body’s ability to metabolize sugar, otherwise known as glucose.
One such medication is Ozempic, an injectable drug approved by the FDA in 2017 to improve blood sugar control in adults with type 2 diabetes. Since its introduction, Ozempic has become widely used—not only for its ability to lower blood sugar but also for a notable side effect: weight loss. While Ozempic is not FDA-approved for weight management, its impact on appetite and metabolism has drawn attention beyond the diabetes community.
In this article, we’ll explore how Ozempic works, its role in diabetes management, and why it has gained so much popularity.
What Is Ozempic — and What Does It Treat?
Ozempic is a medication used to treat type 2 diabetes. It works by improving blood sugar levels over the long term, which is measured by reducing a person’s HbA1c (hemoglobin A1c) levels. Additionally, regular use of Ozempic may help lower the risk of major cardiovascular events like heart attacks and strokes in individuals with type 2 diabetes and heart disease.
How Does Ozempic Work?
The active ingredient in Ozempic, semaglutide, works by mimicking a hormone called glucagon-like peptide-1 (GLP-1). When it activates the GLP-1 receptors, Ozempic enhances your body’s ability to control blood sugar by:
- Telling your pancreas to release insulin when blood sugar is high
- Blocking the release of a hormone called glucagon, which can make your liver release extra sugar into your blood
- Slowing down the rate at which food moves through your intestines, lowering the amount of sugar that enters your bloodstream after you eat
- Making you feel full, leading to less food consumption
Is Ozempic a Weight Loss Aid?
In short, no — although one of the common side effects of Ozempic is its ability to help some users lose weight. In a recent Forbes article, Dr. Christopher McGowan explained that in addition to Ozempic’s effects on blood glucose, the active ingredient, semaglutide, also impacts the hunger centers in the brain, reducing feelings of hunger and food cravings.
While not approved by the FDA as a weight-loss medication, its sister drug, Wegovy, received approval for use by overweight individuals or those with cardiovascular disease in 2021. The key difference between Ozempic and Wegovy is the dosage, with Wegovy offering a higher dose of semaglutide to aid weight loss (alongside a healthy diet and exercise).
So, although the main function of Ozempic isn’t to help people lose weight, its inclusion of semaglutide often results in weight loss as a side effect experienced by many users. Because type 2 diabetes is often associated with obesity, its potential to assist in weight loss may also help individuals manage their condition more effectively and improve their overall health.
Amp Up Your Career in Medicine with a Graduate Credential from UF
Whether you’re interested in a career in drug development or sales and marketing, the University of Florida offers an online master’s degree in medical physiology and pharmacology tailored to helping you achieve your goals in the medical industry.
This entirely online program, developed by two renowned departments at UF, consists of 30 credits divided into two core areas, each comprising 15 credits. The program aims to provide you with an advanced scientific understanding of medical physiology, which focuses on the major human body systems, and medical pharmacology, which examines the impact of drugs on living organisms at the cellular and molecular levels.
With asynchronous courses, you can complete coursework on a timeline that coordinates with your busy schedule, finishing the program in as little as two semesters.
If you’re curious about some of our other medical physiology programs, we have several other specialized programs, depending on your interests and career aspirations, including:
- Master’s Degree in Medical Physiology and Aging
- Graduate Certificate in Medical Physiology
- Graduate Certificate in Medical Physiology with a specialization in Cardiovascular/Renal Physiology
If you have questions about any of our programs, please don’t hesitate to contact us for more information. And when you’re ready to make the first move toward making your career dreams a reality, the application is only a click away.
Sources:
https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/medications-containing-semaglutide-marketed-type-2-diabetes-or-weight-loss
https://www.ozempic.com/why-ozempic/how-ozempic-works.html
https://www.forbes.com/health/weight-loss/ozempic-for-weight-loss/
https://www.fda.gov/news-events/press-announcements/fda-approves-first-treatment-reduce-risk-serious-heart-problems-specifically-adults-obesity-or
What Is Ebola — and How Does It Affect Your Body?
In 1976, researchers first identified a frightening virus that had emerged in the African nation then known as Zaire. While the source of this fast-moving, destructive disease remains unknown, Ebola is believed to have spread to humans from apes, monkeys and bats. There have been several Ebola outbreaks since 1976, primarily in African countries, though the disease has been found in animals originating from Asia as well.
More recently, the most consequential outbreak became a worldwide epidemic: Beginning in Guinea in 2013, the disease spread to other West African countries and later Europe, the United Kingdom and the United States. In the period of two and a half years, Ebola was responsible for killing more than 11,000 people.
In this article, we explore the devastating effects of the Ebola virus on the human body, tracing its progression from initial symptoms to immune system disruption and organ failure.
What Is Ebola?
Ebola is a severe and often fatal disease caused by the Ebola virus. Viewed through a microscope, Ebola looks somewhat like a worm that’s knotted and looped at one end. Like many diseases, it may not be easily recognized by its symptoms, since it shares early symptoms common in many other diseases, including those that indicate a far less serious condition. These symptoms may appear up to three weeks after exposure to the virus and include:
- Fever
- Sore throat
- Aches
- Fatigue
- Vomiting
- Diarrhea
- Unusual bruising
- Bleeding from multiple orifices

How Is Ebola Transmitted?
Humans can contract the virus through contact with infected animal blood and tissue, often via hunting and eating carriers of the disease or being bitten by one of them. The infected individual may then expose others to the disease through their bodily fluids, which can enter the body through a wound, the mucous membranes of the face, or intimate contact. Even a person who has died from Ebola can remain contagious, so their bodies must be handled with care.
What Does Ebola Do Once Inside the Body?
Ebola immediately attacks the immune system that was designed to fight it, leaving immune cells unresponsive, then rapidly replicates itself and spreads through the bloodstream. Other infected immune cells throughout the body cause clots that rob organs of essential blood. The virus does some of its most catastrophic damage by inhibiting plasma production, though other organs and systems are also impacted as the disease makes its way through the body.
Many patients die from Ebola: up to 90%, with an average of 50%. Having quality medical care and a strong immune system can increase one’s odds of recovery. End-stage symptoms may include brain inflammation and organ failure. Medical experts believe that Ebola survivors may develop some immunity, as antibodies stay in their blood for up to a decade.
Discover How Disease and Other Factors Affect Our Body Systems
As you’ve seen, Ebola can wreak havoc throughout the body, impacting many organs and often resulting in death. The University of Florida is proud to offer several entirely online Master of Science programs that provide different perspectives on the body systems, their organs and factors that can affect them. Some of them include:
Master of Science in Medical Sciences with a concentration in Medical Physiology and Pharmacology
Acquire a comprehensive scientific understanding of key human body systems, delve into the effects of drugs on living organisms at cellular and molecular tiers, and explore both normal and abnormal conditions in human body systems. Finish this 30-credit degree program in as little as two semesters.
Master of Science in Medical Sciences with a concentration in Medical Physiology and Aging
Develop a more expansive and profound understanding of the biological processes associated with aging. Finish this 30-credit degree program in as little as one year.
Bring the benefits of a master’s degree in medical physiology to your career!
Sources:
https://time.com/3502740/ebola-virus-1976/
https://www.itg.be/en/health-stories/impact-stories/the-discovery-of-and-research-on-the-ebola-virus
How Does the Immune System Work? 3 Key Strategies
There’s nothing worse than feeling a tinge of discomfort in your throat alerting you that something’s not quite right. When it’s accompanied by a sudden bout of sneezes or a slight fever, you know that it’s time to accept the inevitable: A pathogen has staked its claim in your body, and you’re officially getting sick.
Long before you feel that first tickle, however, your immune system is already hard at work fighting the good fight against the pathogens causing those symptoms.
The immune system has multiple lines of defense designed to help you maintain a clean bill of health, but it’s not an exact science. Occasional illnesses are a part of life, even with a healthy immune system.
Today, we’re dissecting the three strategies the immune system has in place to keep unwanted illnesses at bay.
What Is the Immune System?
When you think of your immune system, what do you see? A tiny but mighty army defending its fortress (a.k.a. you)? You’re not wrong! The immune system is our body’s first wall of defense when we encounter antigens and pathogens attempting to nonchalantly sneak past those defenses.
The immune system is composed of specialized cells that work to identify and eliminate invaders. Like an army, our immune systems use multiple layers of defense to keep those pathogens at bay.
The Immune System’s Three Lines of Defense
What are the three lines of defense in the immune system? And are they akin to defensive tiers in football, where the first line of defense represents the biggest and best and the second and third lines act as backup?
Not quite.
While each line of defense plays a vital role in the immune system’s function, one isn’t inherently more important than the others. Although certain defenses may be more effective against specific pathogens in specific situations, they all collaborate to shield your body from harmful invaders to ensure your well-being.
Below, we break down your immune system’s three primary lines of defense, exploring what makes each one unique and how they work to effectively keep your body safe against pathogens, such as viruses and bacteria.
#1 Physical Barriers
When a pathogen tries to enter your body, the first line of defense it’s up against is our external physical barriers, such as our skin, sweat, saliva and tears. These barriers offer a basic yet effective barrier of protection against unwanted microorganisms.
Other physical barriers include:
- Mucous membranes
These slimy membranes line our nose, throat, intestines and reproductive tract and trap microbes we come into contact with as we breathe and eat.
- Nasal hairs
The hairs inside your nasal cavity have more responsibilities than causing the occasional sneeze. They also trap pathogens and environmental pollutants, such as pollen and dust (hence the sneezing).
- Acidic fluids
Urine, gastric juices and vaginal secretions create low pH conditions, which aren’t hospitable for pathogens and often destroy them.
#2 Innate Immune System
When pathogens bypass the physical barriers, they come across our bodies’ second line of defense: the innate immune system. Rather than targeting particular pathogens, this defense provides an immediate response to any pathogens it detects. Using phagocytes, a broad type of white blood cell, the innate immune system engulfs, digests and eliminates pathogens as they wander through your body.
#3 Adaptive Immune System
While slower acting than the innate immune system, the final line of defense—the adaptive immune system— often defends your body with more precision. It works by using memory cells that target germs you’ve encountered previously, thus providing a quick response upon being re-exposed.
The adaptive immune system is why we usually get certain illnesses, like chicken pox, just once in our lives. After fighting off the virus, our bodies build a natural immunity to it, recognizing it the next time our bodies come into contact with it and destroying it on site.
The adaptive immune response begins with dendritic cells, which capture and present fragments of the pathogen to helper T cells in nearby lymph nodes. The helper T cells send signals to other immune cells known as B cells, telling them to produce the antibodies that will target the invading pathogen. This creates memory cells that can recognize and neutralize the threat if you’re re-exposed to it.
The University of Florida: Your Pathway to Success
While each line of defense may be referred to as first, second and third, they all play crucial roles in maintaining our body’s health against COVID-19, the flu, the common cold and other viruses.
Understanding the importance of these defenses can inspire individuals to pursue careers in immunology and related fields. If you’re interested in developing vaccines or becoming involved in cutting-edge medical research, the University of Florida offers several online graduate programs tailored to help you achieve your professional goals. Some of them include:
- Master’s Degree in Medical Physiology and Pharmacology
- Master’s Degree in Medical Physiology and Aging
- Graduate Certificate in Medical Physiology
- Graduate Certificate in Medical Physiology with a specialization in Cardiovascular/Renal Physiology
All of our programs offer online students the following advantages:
- Asynchronous classes that allow you to complete your coursework on your schedule
- Year-round start dates
- No GRE requirements
- Affordable tuition costs
- A renowned education from U.S. News’ top 10 public universities in the nation
Discover the program that aligns with your passions, and start your application today!
Sources:
https://www.news-medical.net/health/What-are-the-Three-Lines-of-Defense.aspx
https://www.ncbi.nlm.nih.gov/books/NBK279396/
How Do Organs Communicate With Each Other?
Picture this: You’re reaching into the oven to take out a tray of freshly baked cookies. As you’re pulling it out, the kitchen towel you’re using shifts, causing you to burn one of your fingers. Your initial reaction is to acknowledge the pain of the burn, but soon after, your body kicks into gear to repair the damaged skin.
As entertaining as it might be to picture one body part shouting to the other, “Oi, I’ve been burned! Increase the blood flow to limit the damage!” that’s not how organ communication occurs. Rather, your organs use their own methods of internal, nonverbal communication to ensure your body is functioning at its optimal level.
Below, we discuss three types of communication that organs use to exchange vital information and explain the importance of their continued reliable interactions.
What Are the Different Types of Organ Communication?
Before we can fully understand how organs communicate with one another, we need to ask ourselves another critical question: How do cells within an organism communicate with each other? Given that cells are the building blocks that make up tissues and organs, it’s a logical place to start. Simply put, human cells communicate through cell chemical signaling, where molecules such as neurotransmitters, cytokines and hormones are released from one cell and accepted by another. Through chemical signaling, the body can coordinate numerous physiological processes, from repairing tissue to regulating metabolism.
Below, we explore three common internal communication methods our organs use daily.
#1 Endocrine Communication
When your body needs to communicate with organs on the other side of the body, it relies on endocrine communication. Let’s use the burn example from earlier to learn how this type of communication works.
After your skin comes into contact with the hot baking sheet, specialized nerves called nociceptors detect tissue damage and send electrical signals to your brain, signaling pain from the burn. This marks the beginning of endocrine communication.
From there, your body interprets the burn as a stressor, prompting the hypothalamus, a region in the lower forebrain, to release a corticotropin-releasing hormone (CRH) into the bloodstream. The CRH triggers the pituitary gland in a different part of your body to release a different hormone. In response, your adrenal glands release cortisol, which aids in stress management and decreases pain perception by reducing pain signals on the nociceptors.
#2 Paracrine Communication
When one organ needs to relay information to a nearby organ, it uses paracrine communication. This type of cell signaling happens when a cell releases a chemical that targets nearby cells or tissues to accomplish a specific task.
Let’s explore how your body uses paracrine communication once it registers the pain from the burn. Internally, your body works to reduce damage and prevent infection by starting the healing process through inflammation. To trigger inflammation, your body uses paracrine communication to signal nearby immune cells to act as first responders and release signaling molecules called cytokines. These cytokines then send messages to other cells close by, recruiting immune cells to start the inflammatory response.
#3 Autocrine Communication
Your body uses autocrine communication when organs need to send messages to themselves. That’s right, sometimes they need to alert themselves that it’s time to complete a new task. For example, once the inflammation on your hypothetical burn has subsided, it’s time for your skin cells to repair themselves by replacing damaged tissue, replacing it with fresh skin cells.
In this instance, the cells on your skin would secrete a hormone that binds to the receptors within the same cell. The result would be a change in the function of the cell, stimulating healing processes, such as cell division and protein synthesis, leading to the growth of new cells to heal the wound.
Why Is Communication Between Organs Important?
Of course, the communication of organs goes much deeper than the occasional first-degree kitchen burn. There are several other important functions that your body completes with the help of its specialized internal communication strategies, including:
Homeostasis
Our bodies self-regulate to maintain internal equilibrium, even when external conditions, like the temperature, fluctuate each day. This process is known as homeostasis. Organ communication plays a key role in regulating our body’s temperature, pH and nutrient levels.
For example, after eating, your blood sugar levels begin to rise. To maintain a regulated blood sugar level, the pancreas releases insulin into the bloodstream through endocrine communication. Insulin acts as a messenger, telling cells throughout the body to absorb glucose from the bloodstream to be used for later use.
Disease prevention and management
When the communication between organs deteriorates, it can contribute to the development of various health conditions. Take the insulin example from above: If the pancreas doesn’t signal for the release of insulin in a timely fashion, the body becomes more susceptible to diabetes.
Your Path to an Advanced Career in Medicine Starts at UF
Gaining a deeper understanding of how organs communicate gives the scientific community insight into how diseases work, aiding in the development of targeted treatments. Whether you’re embarking on a new career in medicine or seeking opportunities to enhance your resume for medical school applications, UF offers nine online programs in the medical sciences to support your journey toward a health-related profession. These graduate programs include:
- Master’s Degree in Medical Physiology and Pharmacology
- Master’s Degree in Medical Physiology and Aging
- Graduate Certificate in Medical Physiology
- Graduate Certificate in Cardiovascular and Renal Physiology
Our programs are entirely online, so you have the flexibility to work at your own pace. We also accept students year-round, so you can start this exciting new chapter when the time is right.
When you’re ready, take the first step and apply to the medical physiology program that aligns with your career aspirations.
Sources:
https://www.ncbi.nlm.nih.gov/books/NBK26813/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964977/
https://journals.lww.com/pain/abstract/2019/08000/cortisol_affects_pain_sensitivity_and_pain_related.7.aspx
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938527/
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/cytokine
https://www.cdc.gov/diabetes/basics/insulin-resistance.html